Diurnal Variation of Adrenocortical Activity in Chronic Fatigue Syndrome

  title={Diurnal Variation of Adrenocortical Activity in Chronic Fatigue Syndrome},
  author={Siobhan Machale and Jonathan Cavanagh and J. G. Bennie and S. Carroll and Guy M. Goodwin and Stephen M. Lawrie},
  pages={213 - 217}
Baseline morning and evening serum cortisol and ACTH concentrations, and diurnal changes in hormone levels, were measured in 30 patients with chronic fatigue syndrome (CFS) but without concurrent depressive disorder and a control group of 15 weight-, age- and sex-matched healthy volunteers. Morning cortisol levels were non-significantly lower in CFS patients, while evening levels were non-significantly higher. ACTH concentrations were non-significantly higher in both the morning and evening… 

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