Diuretic induced hypokalaemia: relationship to dosage interval and plasma aldosterone.

Abstract

Plasma potassium and aldosterone responses to 9 days treatment with hydrochlorothiazide (100 mg/day) alone or in combination with spironolactone (100 mg/day), prescribed once daily or in doses 12 h apart, were examined in a double-blind, crossover study in twelve healthy subjects. Plasma potassium concentrations were lower when the drugs were administered… (More)

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Cite this paper

@article{McInnes1982DiureticIH, title={Diuretic induced hypokalaemia: relationship to dosage interval and plasma aldosterone.}, author={G. T. McInnes and J. Roger Shelton and I. Harrison and Robert M. Perkins and Gorgi Rigby}, journal={British journal of clinical pharmacology}, year={1982}, volume={14 3}, pages={449-52} }