Disynaptic Effect of Hilar Cells on Pattern Separation in A Spiking Neural Network of Hippocampal Dentate Gyrus

  title={Disynaptic Effect of Hilar Cells on Pattern Separation in A Spiking Neural Network of Hippocampal Dentate Gyrus},
  author={Sang-Yoon Kim and Woochang Lim},
  • Sang-Yoon Kim, Woochang Lim
  • Published 24 September 2021
  • Biology, Physics
  • bioRxiv
We investigate the disynaptic effect of the hilar cells on pattern separation in a spiking neural network of the hippocampal dentate gyrus (DG). The principal granule cells (GCs) in the DG perform pattern separation, transforming similar input patterns into less-similar output patterns. In our DG network, the hilus consists of excitatory mossy cells (MCs) and inhibitory HIPP (hilar perforant path-associated) cells. Here, we consider the disynaptic effects of the MCs and the HIPP cells on the… Expand


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  • Sang-Yoon Kim, W. Lim
  • Medicine, Chemistry
  • Neural networks : the official journal of the International Neural Network Society
  • 2020
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