Disulfiram impairs the development of behavioural sensitization to the stimulant effect of ethanol.


BACKGROUND Although disulfiram has been used in the treatment of alcoholism due to the unpleasant sensations its concomitant ingestion with ethanol provokes, some patients reported stimulant effects after its ingestion. This issue has not been addressed in studies with animals. In mice, the stimulant effect of ethanol has been associated with increased… (More)
DOI: 10.1016/j.bbr.2009.10.032


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