Disulfide Bond Formation and Cysteine Exclusion in Gram-positive Bacteria*♦

  title={Disulfide Bond Formation and Cysteine Exclusion in Gram-positive Bacteria*♦},
  author={Robert Daniels and Peter Mellroth and Andreas Bernsel and Fabrice Neiers and Staffan J. Normark and Gunnar von Heijne and Birgitta Henriques-Normark},
  booktitle={The Journal of biological chemistry},
Most secretion pathways in bacteria and eukaryotic cells are challenged by the requirement for their substrate proteins to mature after they traverse a membrane barrier and enter a reactive oxidizing environment. For Gram-positive bacteria, the mechanisms that protect their exported proteins from misoxidation during their post-translocation maturation are poorly understood. To address this, we separated numerous bacterial species according to their tolerance for oxygen and divided their… CONTINUE READING

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