Disturbed emotionality in autoimmune MRL-lpr mice

@article{aki1994DisturbedEI,
  title={Disturbed emotionality in autoimmune MRL-lpr mice},
  author={Boris {\vS}aki{\'c} and Henry Szechtman and Hazel Talangbayan and Susan D. Denburg and Ramona M. Carbotte and Judah A. Denburg},
  journal={Physiology & Behavior},
  year={1994},
  volume={56},
  pages={609-617}
}
MRL-lpr mice develop symptoms of autoimmune lupus-like disease early in the life and MRL(-)+/+ mice develop it substantially later. The present study examines our previous suggestion that autoimmune MRL-lpr mice show altered emotional reactivity. In addition, it aims to identify the set of measures which best discriminate the behavior of MRL-lpr mice from their congenic controls (MRL +/+). Behavior of males from these two substrains (n = 40/substrain; 3-4 mo of age) was compared on a battery of… CONTINUE READING
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