Disturbances in acute phase plasma proteins during melancholia: Additional evidence for the presence of an inflammatory process during that illness

@article{Maes1992DisturbancesIA,
  title={Disturbances in acute phase plasma proteins during melancholia: Additional evidence for the presence of an inflammatory process during that illness},
  author={Michael Maes and Simon S Scharp{\'e} and Eug{\`e}ne Bosmans and Maurits Vandewoude and Jef Raus},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={1992},
  volume={16},
  pages={501-515}
}
1. Leukocyte enumeration through flow cytometry has revealed that severe depression may be accompanied by a systemic immune activation, indicative of an inflammatory response. The latter condition allegedly involves an important modification of acute phase plasma protein (APP) equilibrium. 2. In order to elucidate whether the state of severe depression is represented by alterations in APPs, the authors measured: alpha 1 antitrypsin (alpha 1 AT), alpha 2 macroglobulin (alpha 2 M), haptoglobin… CONTINUE READING

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