Disturbance of thalamic metabolism and its association with regional neural dysfunction and cognitive impairment in minimal hepatic encephalopathy.

@article{Chen2020DisturbanceOT,
  title={Disturbance of thalamic metabolism and its association with regional neural dysfunction and cognitive impairment in minimal hepatic encephalopathy.},
  author={L. Chen and Jia-Yan Shi and Tian-Xiu Zou and L. Zhang and Y. Gou and Yanqin Lin and Hua-jun Chen},
  journal={European journal of radiology},
  year={2020},
  volume={131},
  pages={
          109252
        }
}
PURPOSE To conduct the first investigation on thalamic metabolic alterations in minimal hepatic encephalopathy (MHE) and elucidate their association with intrinsic neural activity change and cognitive dysfunction. METHODS Thirty-eight cirrhotic patients [18 with MHE, 20 without MHE (NHE)] and 21 healthy controls (HC) were included, all of whom underwent 1H-magnetic resonance spectroscopy, resting-state functional magnetic resonance imaging (fMRI), as well as cognitive assessment based on the… Expand

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