Distributional characteristics of sulfated glycosaminoglycans in normal human nasal mucosa and nasal polyp.

@article{Lee2005DistributionalCO,
  title={Distributional characteristics of sulfated glycosaminoglycans in normal human nasal mucosa and nasal polyp.},
  author={Sang Hag Lee and Joon Whan Oh and Heung M. Lee and Hak Hyun Jung and Seung Hoon Lee and Ji Won Jang and Hyun Soo Jhun and Young Joon Jhun},
  journal={Acta oto-laryngologica},
  year={2005},
  volume={125 10},
  pages={
          1075-9
        }
}
  • Sang Hag Lee, Joon Whan Oh, +5 authors Young Joon Jhun
  • Published in Acta oto-laryngologica 2005
  • Biology, Medicine
  • The results of this study suggest that an altered expression pattern of sulfated glycosaminoglycans (GAGs) in nasal polyp may not function as a charge restriction barrier for vascular permeability, contributing to the leakage of protein and fluid. Sulfated GAGs are found on the vascular endothelial surface and in the extracellular matrix in various tissues and organs, suggesting that these materials constitute a negatively charged screen restricting the movement of circulating plasma molecules… CONTINUE READING

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