Distribution study of a synthetic ACTH analogue in rat tissue.

  title={Distribution study of a synthetic ACTH analogue in rat tissue.},
  author={Masaharu Hirata and Shinya Futaguchi and Kunihiro Odaguchi and K Inouye and Akira Tanaka},
  journal={Acta endocrinologica},
  volume={96 4},
Tissue distribution of (Aib1, Lys17, 18, 19)-corticotrophin-(1-19)-nonadecapeptide amide (690024-S), iv injected to hypophysectomized rats, were surveyed by bioassay. Among the tissues examined. the largest amount of 690024-S was found in the liver during 3 h of search for the injection, while a higher concentration of the peptide per tissue weight was found in kidney. Though a small amount of 690024-S was detected in spleen, heart and lung at an early stage, it was not detectable in other… 

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