Distribution of vitellogenin in zebrafish (Danio rerio) tissues for biomarker analysis.

  title={Distribution of vitellogenin in zebrafish (Danio rerio) tissues for biomarker analysis.},
  author={Liqiao Zhong and Li Yuan and Yu Rao and Zhouquan Li and Xiaohua Zhang and Tao Liao and Ying Xu and Heping Dai},
  journal={Aquatic toxicology},
Vitellogenin (VTG), the precursor of yolk proteins, is a sensitive biomarker of estrogenic contamination in aquatic environments. Traditionally, VTG was believed to be synthesized under the control of estrogen in the livers of mature females and then secreted into the blood, before being taken up by the ovaries and cleaved into lipovitellin and phosvitin, which provide nutrition for developing embryos. However, recent studies have reported that the liver is not the only tissue to express VTG… CONTINUE READING
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