Distribution of ventilation-perfusion ratios in dogs with normal and abnormal lungs.

@article{Wagner1975DistributionOV,
  title={Distribution of ventilation-perfusion ratios in dogs with normal and abnormal lungs.},
  author={Peter D. Wagner and Raymond B. Laravuso and E Goldzimmer and P F Naumann and John B. West},
  journal={Journal of applied physiology},
  year={1975},
  volume={38 6},
  pages={1099-109}
}
We have recently described a new method for measuring distributions of ventilation-perfusion ratios (VA/Q) based on inert gas elimination. Here we report the initial application of the method in normal dogs and in dogs with pulmonary embolism, pulmonary edema, and pneumonia. Characteristic distributions appropriate to the known effects of each lesion were observed. Comparison with traditional indices of gas exchange revealed that the arterial PO2 calculated from the distributions agreed well… CONTINUE READING

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