Distribution of type I collagen morphologies in bone: relation to estrogen depletion.

@article{Wallace2010DistributionOT,
  title={Distribution of type I collagen morphologies in bone: relation to estrogen depletion.},
  author={Joseph M Wallace and Blake Erickson and Clifford M. Les and Bradford G. Orr and Mark M Banaszak Holl},
  journal={Bone},
  year={2010},
  volume={46 5},
  pages={
          1349-54
        }
}
Bone is an amazing material evolved by nature to elegantly balance structural and metabolic needs in the body. Bone health is an integral part of overall health, but our lack of understanding of the ultrastructure of healthy bone precludes us from knowing how disease may impact nanoscale properties in this biological material. Here, we show that quantitative assessments of a distribution of Type I collagen fibril morphologies can be made using atomic force microscopy (AFM). We demonstrate that… CONTINUE READING
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