Distribution of tumor-sensitized cells during the induction of permanent tumor regression by chemoimmunotherapy: the use of glucose phosphate isomerase as a marker.

@article{Evans1984DistributionOT,
  title={Distribution of tumor-sensitized cells during the induction of permanent tumor regression by chemoimmunotherapy: the use of glucose phosphate isomerase as a marker.},
  author={Robert Evans and Theodore M. Duffy},
  journal={International journal of cancer},
  year={1984},
  volume={34 4},
  pages={575-80}
}
Using a previously described tumor model system, in which permanent tumor eradication was induced by treatment with cyclophosphamide (CY) and adoptively transferred tumor-sensitized (immune) spleen cells, we determined the distribution of the transferred cells in recipient mice. The experiments were carried out using the C57BL/6J (B6) sarcoma, MCA/76-9, and B6 and congeneic B6.CAST.Gpi-Ia strains, which are homozygous for the glucose phosphate isomerase (Gpi) alleles Ib and Ia respectively… CONTINUE READING