Distribution of tumor antigen in cell fractions of adenovirus 12-induced tumor--its application to fluorescent antibody technique.

  • T Okamoto
  • Published 1969 in Acta medicinae Okayama

Abstract

Adl2-induced tumors were homogenized and fractionated by the SCHNEIDER’S method. The CF test with the serum from tumor-bearing hamsters revealed the predominant presence of T-antigen in the mitochondrial and microsomal fractions. Hence, the rabbit was immunized with the microsomal fraction of tumors, and its serum was used to prepare the fluorescent… (More)

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