Distribution of thyrotropin-releasing hormone receptor messenger RNA in the rat brain: an in situ hybridization study.

@article{Calz1992DistributionOT,
  title={Distribution of thyrotropin-releasing hormone receptor messenger RNA in the rat brain: an in situ hybridization study.},
  author={Laura Calz{\`a} and Luciana Giardino and Sandra Ceccatelli and Massimo Zanni and Robert Elde and Tomas G M H{\"o}kfelt},
  journal={Neuroscience},
  year={1992},
  volume={51 4},
  pages={891-909}
}
Based on the recent cloning of the mouse thyrotropin-releasing hormone receptor, oligonucleotide probes complementary to the DNA sequence were constructed and used for in situ hybridization studies on the rat brain. Thyrotropin-releasing hormone receptor messenger RNA was found in many areas of the brain, mostly showing high degree of overlap with the distribution thyrotropin-releasing hormone binding sites as previously revealed in autoradiographic studies. Thus, a strong signal was observed… CONTINUE READING

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