• Corpus ID: 1420617

Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues.

  title={Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues.},
  author={Steven D. Weitman and R H Lark and Leslie R. Coney and Daniel W. Fort and Verna Frasca and Vincent R. Zurawski and Barton A. Kamen},
  journal={Cancer research},
  volume={52 12},
In some epithelial cells studied in vitro a membrane-bound folate receptor initiates the process for cell accumulation of 5-methyltetrahydrofolic acid. This receptor was found to be GP38, an overexpressed, glycosyl-phosphatidylinositol anchored glycoprotein, recognized by two monoclonal antibodies, designated MOv18 and MOv19. Using immunoblotting with MOv19, radioimmunoassay with MOv18 and 19, Northern blot analysis, and radioligand binding when possible, we describe the limited expression of… 

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