Distribution of tenascin in oral premalignant lesions and squamous cell carcinoma.

@article{Tiitta1994DistributionOT,
  title={Distribution of tenascin in oral premalignant lesions and squamous cell carcinoma.},
  author={O. Tiitta and R P Happonen and Ismo Virtanen and Marita Luomanen},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  year={1994},
  volume={23 10},
  pages={446-50}
}
The distribution of the extracellular matrix (ECM) protein tenascin (Tn) was studied in oral premalignant lesions and squamous cell carcinoma by using the monoclonal antibody (Mab) 143DB7. In normal buccal and palatal mucosa, in ventral tongue, in floor of mouth and in gingiva, immunoreaction for Tn was seen to be distributed as a continuous thin, delicate line merely in the basement membrane region. Hyperkeratosis without dysplasia showed a distinct zone of enhanced Tn immunoreactivity… CONTINUE READING
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