Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation

  title={Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation},
  author={Florence Nicole Schleich and Mait{\'e} Manise and Jocelyne Sele and Monique A Henket and Laurence Seidel and Renaud E Louis},
  booktitle={BMC pulmonary medicine},
BACKGROUND Phenotyping asthma according to airway inflammation allows identification of responders to targeted therapy. Induced sputum is technically demanding. We aimed to identify predictors of sputum inflammatory phenotypes according to easily available clinical characteristics. METHODS This retrospective study was conducted in 508 asthmatics with successful sputum induction recruited from the University Asthma Clinic of Liege. Receiver-operating characteristic (ROC) curve and multiple… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 13 times. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 41 extracted citations

Patient stratification and the unmet need in asthma.

Pharmacology & therapeutics • 2017
View 4 Excerpts
Highly Influenced

Asthma Endotyping and Biomarkers in Childhood Asthma

Pediatric allergy, immunology, and pulmonology • 2018

Establishment of different experimental asthma models in mice

Experimental and therapeutic medicine • 2018
View 1 Excerpt

Diagnostic utility of fractional exhaled nitric oxide in prolonged and chronic cough according to atopic status.

Allergology international : official journal of the Japanese Society of Allergology • 2017


Publications referenced by this paper.
Showing 1-10 of 40 references

A large subgroup of mild-to-moderate asthma is persistently noneosinophilic.

American journal of respiratory and critical care medicine • 2012
View 3 Excerpts
Highly Influenced

Induced Sputum - Towards Normal Values. Non Invasive Assessment of airways inflammation in asthma and COPD

R Louis, L Godinas, F Schleich
14th, tetrapoleos street, Athens, • 2011
View 1 Excerpt

Association between asthma control and bronchial hyperresponsiveness and airways inflammation: a cross-sectional study in daily practice.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…