Distribution of somatostatin receptor messenger RNAs in the rat gastrointestinal tract.

@article{Krempels1997DistributionOS,
  title={Distribution of somatostatin receptor messenger RNAs in the rat gastrointestinal tract.},
  author={K-H. Krempels and B{\'e}la Hunyady and Anne O'CARROLL and {\'E}va Mezey},
  journal={Gastroenterology},
  year={1997},
  volume={112 6},
  pages={1948-60}
}
BACKGROUND & AIMS The gastrointestinal (GI) tract is a major source and target of somatostatin (SRIF). Recently, five pharmacologically different SRIF receptors (sst1-5) were cloned. The cellular and tissue distribution of the sst1-5 messenger RNAs (mRNAs) were studied in the rat GI tract using in situ hybridization histochemistry (ISHH). METHODS Two sets of (35)S-uridine triphosphate (UTP)-labeled antisense and sense riboprobes were prepared for each sst. ISHH was conducted on frozen tissue… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…