Distribution of penicillin-G and spiramycin to tissue cages and subcutaneous tissue fluid in calves.

@article{Bengtsson1991DistributionOP,
  title={Distribution of penicillin-G and spiramycin to tissue cages and subcutaneous tissue fluid in calves.},
  author={Bj{\"o}rn Bengtsson and Anders Franklin and S. O. Jacobsson and J. Luthman and M Horn af Rantzien},
  journal={Research in veterinary science},
  year={1991},
  volume={50 3},
  pages={
          301-7
        }
}
Antibacterial drug concentrations in serum, tissue cage fluid (TCF) and subcutaneous tissue fluid (SF), sampled either by filter paper discs or by microcapillaries, were measured after single intramuscular injections of potassium penicillin-G (KPG), procaine penicillin-G (PPG) and spiramycin adipate in calves. Concentration-time curves had essentially similar profiles in serum and SF, but peak levels were lower and occurred later in SF. From approximately four hours after drug administration… CONTINUE READING

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