Distribution of pancreatic polypeptide and peptide YY

@article{Ekblad2002DistributionOP,
  title={Distribution of pancreatic polypeptide and peptide YY},
  author={Eva Ekblad and Frank Sundler},
  journal={Peptides},
  year={2002},
  volume={23},
  pages={251-261}
}
Peptide YY: A neuroendocrine neighbor of note
Regulation of Pancreatic Secretion
TLDR
The physiological effects of specific neurotransmitters and enteric hormones that stimulate or inhibit the pancreas are described and these mechanisms are used to understand the physiological basis and utility of pancreatic function testing.
Molecular cloning, tissue and embryonic development expression, and appetite regulatory effect of pancreatic peptide Y in Coilia nasus
TLDR
A potential role for PY in appetite regulation is revealed and provides a basis for further study of Py in C. nasus, suggesting a potential relationship between food intake and the expression of PY.
Immunolocalization of the PP family and its receptors in the gastrointestinal tract of house musk shrew, Suncus murinus.
TLDR
Investigation of the immunolocalization of the pancreatic polypeptide (PP)-fold peptide family, important regulatory factors for food intake, in the gastrointestinal tract of Suncus murinus found the PP family and their receptor-producing cells were predominantly distributed at the end of theintestinal tract, the rectum.
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References

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The distribution and ontogeny of polypeptide YY (PYY)-and pancreatic polypeptide (PP)-immunoreactive cells in the gastrointestinal tract of rat
TLDR
The difference between PYY-and PP-immunoreactive cells in the distribution, frequency and ontogeny provide further evidence that PYY and PP occur in two independent cell types.
Immunocytochemical identification of polypeptide YY (PYY) cells in the human gastrointestinal tract
TLDR
Staining of consecutive thin plastic sections and staining of the same section simultaneously for two peptides showed that PYY-immunoreactivity did not occur in PP- or enteroglucagon-immonoreactive cells.
Localization of peptide YY (PYY) in gastrointestinal endocrine cells and effects on intestinal blood flow and motility.
TLDR
It is concluded that PYY is a gastrointestinal peptide that is present mainly in endocrine cells of distal intestine and that has effect on both intestinal motility and the cardiovascular system.
Peptide YY (PYY) immunoreactivity is co-stored with glucagon-related immunoreactants in endocrine cells of the gut and pancreas
TLDR
The localisation of PYY immunoreactivity in intestinal mucosa endocrine (EG) cells containing glucagon-related peptides and also in foetal pancreatic A cells of rat and man is reported.
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