Distribution of p53 codon 72 polymorphisms in ovarian tumour patients and their prognostic significance in ovarian cancer patients.

@article{Hgdall2002DistributionOP,
  title={Distribution of p53 codon 72 polymorphisms in ovarian tumour patients and their prognostic significance in ovarian cancer patients.},
  author={Estrid V. S. H\ogdall and Claus Kim H\ogdall and Lise Christensen and Eva Glud and Jan Blaakaer and Johannes E. Bock and Jens Vuust and Bent N\orgaard-Pedersen and Susanne Kr{\"u}ger Kjaer},
  journal={Anticancer research},
  year={2002},
  volume={22 3},
  pages={1859-64}
}
BACKGROUND The p53 gene is frequently mutated in various human tumours. In addition, single nucleotide polymorphisms are often observed in exons and introns of the p53 gene in normal tissues and tumours. MATERIALS AND METHODS The prevalence of a polymorphism involving codon 72 of exon 4 in the p53 gene was studied in peripheral white blood cells and tumour tissues from Danish ovarian tumour patients and in peripheral white blood cells from controls. The analyses were performed by Polymerase… CONTINUE READING
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