Distribution of p230, an alpha-spectrin-related polypeptide in normal and psoriatic epidermis and in cultured human keratinocytes.

@article{Kariniemi1984DistributionOP,
  title={Distribution of p230, an alpha-spectrin-related polypeptide in normal and psoriatic epidermis and in cultured human keratinocytes.},
  author={Arja Leena Kariniemi and V. P. Lehto and Ismo Virtanen},
  journal={The British journal of dermatology},
  year={1984},
  volume={111 2},
  pages={139-45}
}
We studied the localization of p230, an immunoanalogue of erythroid alpha-spectrin, in normal and psoriatic human epidermis and in cultured human keratinocytes. In immunofluorescence microscopy of frozen sections of normal skin a bright cytoplasmic staining was seen in the cortical area of the keratinocytes. Similar staining was also seen in lesional and uninvolved areas of psoriatic epidermis. The pericytoplasmic localization of p230 could also be seen in cultured human keratinocytes: a lamina… CONTINUE READING