Distribution of neutral endopeptidase activity in human blood leukocytes.

  title={Distribution of neutral endopeptidase activity in human blood leukocytes.},
  author={Itsuo Iwamoto and Akira Kimura and Kazunori Ochiai and Haruaki Tomioka and Sho Yoshida},
  journal={Journal of leukocyte biology},
  volume={49 2},
We investigated the distribution of neutral endopeptidase (NEP; EC activity, a possible regulatory enzyme for neuropeptide-induced leukocyte activations, in each cell type of human blood leukocytes. The NEP activity assessed by an NEP inhibitor phosphoramidon-sensitive Met5-enkephalin degrading activity was present in neutrophils and the common acute lymphoblastic leukemia antigen (CALLA)-positive leukemic cells (59 pmol/min/10(6) cells and 62 pmol/min/10(6) cells, respectively… CONTINUE READING
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Substance P ( SP ) enhances IgEdependent human basophil histamine release ( HR )

  • CA. Swenson, W. W. Busse
  • J . Allergy Clin . Immunol .
  • 1989

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