Distribution of neutral endopeptidase activity in human blood leukocytes.

@article{Iwamoto1991DistributionON,
  title={Distribution of neutral endopeptidase activity in human blood leukocytes.},
  author={Itsuo Iwamoto and Akira Kimura and Kazunori Ochiai and Haruaki Tomioka and Sho Yoshida},
  journal={Journal of leukocyte biology},
  year={1991},
  volume={49 2},
  pages={116-25}
}
We investigated the distribution of neutral endopeptidase (NEP; EC 3.4.24.11) activity, a possible regulatory enzyme for neuropeptide-induced leukocyte activations, in each cell type of human blood leukocytes. The NEP activity assessed by an NEP inhibitor phosphoramidon-sensitive Met5-enkephalin degrading activity was present in neutrophils and the common acute lymphoblastic leukemia antigen (CALLA)-positive leukemic cells (59 pmol/min/10(6) cells and 62 pmol/min/10(6) cells, respectively… CONTINUE READING
9 Extracted Citations
54 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-9 of 9 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 54 references

Substance P ( SP ) enhances IgEdependent human basophil histamine release ( HR )

  • CA. Swenson, W. W. Busse
  • J . Allergy Clin . Immunol .
  • 1989

Similar Papers

Loading similar papers…