Distribution of myofibroblasts, smooth muscle-like cells, macrophages, and mast cells in mitral valve leaflets of dogs with myxomatous mitral valve disease.

@article{Han2008DistributionOM,
  title={Distribution of myofibroblasts, smooth muscle-like cells, macrophages, and mast cells in mitral valve leaflets of dogs with myxomatous mitral valve disease.},
  author={Richard I. Han and A. W. Black and Geoff J Culshaw and Anne T. French and Roderick W. Else and Brendan M. Corcoran},
  journal={American journal of veterinary research},
  year={2008},
  volume={69 6},
  pages={763-9}
}
OBJECTIVE To map the cellular distribution and phenotypic alteration of the predominant stromal cell population throughout the entire valve length of dogs with myxomatous mitral valve disease (MMVD). SAMPLE POPULATION 31 mitral valve complexes (ie, mitral valve leaflets) collected from 4 clinically normal dogs and 27 dogs with MMVD of varying severity. PROCEDURES A combination of standard histologic and immunohistochemical techniques was used to identify pathologic changes, the presence of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 21 references

The cardiac valve interstitial cell

  • WM Lester, AA Damji, I Gedeon
  • Int J Biochem Cell Biol
  • 2003

Similar Papers

Loading similar papers…