Distribution of mu-opioid receptors in the nucleus raphe magnus and nucleus gigantocellularis: a quantitative autoradiographic study.

@article{Bowker1988DistributionOM,
  title={Distribution of mu-opioid receptors in the nucleus raphe magnus and nucleus gigantocellularis: a quantitative autoradiographic study.},
  author={Robert M. Bowker and Roger P. Dilts},
  journal={Neuroscience letters},
  year={1988},
  volume={88 3},
  pages={247-52}
}
The present study has described and quantitated the distribution of mu-opioid receptors in the nucleus raphe magnus (NRM) and nucleus gigantocellularis (NGC), using in vitro autoradiography. Moderately dense binding of a mu-enkephalin analog, DAGO, was observed in the NRM and adjacent parts of the NGC. DAGO binding density was greatest in the anterior NRM, possibly due to a greater involvement in the descending, opiate-mediated modulation of nociception. These findings agree with proposed roles… CONTINUE READING
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