Distribution of keratins in normal endothelial cells and a spectrum of vascular tumors: implications in tumor diagnosis.

@article{Miettinen2000DistributionOK,
  title={Distribution of keratins in normal endothelial cells and a spectrum of vascular tumors: implications in tumor diagnosis.},
  author={Markku M. Miettinen and John F. Fetsch},
  journal={Human pathology},
  year={2000},
  volume={31 9},
  pages={1062-7}
}
Vascular endothelial cells are specialized mesenchyme-derived epithelial-like lining cells which are the essential participants in benign and malignant vascular tumors. Although endothelia in lower animals often express keratins (K), human endothelia are generally K negative and vimentin-positive. However, K expression has been noted in some endothelia and in some epithelioid vascular tumors. In this study, we systematically examined normal human vascular endothelia and a spectrum of human… CONTINUE READING

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