Distribution of ions in a fluid-transporting epithelium determined by electron-probe X-ray microanalysis

@article{Gupta1976DistributionOI,
  title={Distribution of ions in a fluid-transporting epithelium determined by electron-probe X-ray microanalysis},
  author={Brij L. Gupta and Theodore A. Hall and S H P Maddrell and Roger B. Moreton},
  journal={Nature},
  year={1976},
  volume={264},
  pages={284-287}
}
STUDIES of fluid transport in epithelia have in general been limited to measurements of the composition of the transported fluid and the electrochemical gradients against which transport occurs1–3. We have now used electron-probe X-ray microanalysis to measure the intracellular ionic concentrations. The data show that Na, K and Cl are not uniformly distributed within the cells; that the basal lamina is not entirely a passive membrane open to small ions, and that, in the particular epithelium… CONTINUE READING
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