Distribution of interstitial stem cells in Hydra.

  title={Distribution of interstitial stem cells in Hydra.},
  author={Charles N. David and I J Plotnick},
  journal={Developmental biology},
  volume={76 1},
The distribution of interstitial stem cells along the Hydra body column was determined using a simplified cloning assay. The assay measures stem cells as clone-forming units (CFU) in aggregates of nitrogen mustard inactivated Hydra tissue. The concentration of stem cells in the gastric region was uniform at about 0.02 CFU/epithelial cell. In both the hypostome and basal disk the concentration was 20-fold lower. A decrease in the ratio of stem cells to committed nerve and nematocyte precursors… CONTINUE READING