Distribution of interstitial cells of Cajal in the neurogenic urinary bladder of children with myelomeningocele.

PURPOSE C-kit positive interstitial cells of Cajal (ICCs) play an important role in the regulation of the smooth muscle motility, acting as pacemakers to provide the slow wave activity in various organs. Recent studies have shown that c-kit positive ICCs are widely distributed in the urinary tract of animals and humans. The aim of our study was to examine… CONTINUE READING