Distribution of injected iron 59 and manganese 54 in hypotransferrinemic mice.

@article{Dickinson1996DistributionOI,
  title={Distribution of injected iron 59 and manganese 54 in hypotransferrinemic mice.},
  author={Tanya Dickinson and Attila G. Devenyi and James R. Connor},
  journal={The Journal of laboratory and clinical medicine},
  year={1996},
  volume={128 3},
  pages={
          270-8
        }
}
Transferrin has been proposed as the mobilization protein for iron and manganese. To better understand the role of transferrin in the transport of these metals, we studied the tissue distribution of injected iron 59 and manganese 54 in the hypotransferrinemic (Hp) mouse mutant. The Hp mouse has a mutation in the transferrin gene and produces < 1% of normal transferrin levels. The tissue distribution of 59Fe and 54Mn in Hp mice was compared with that in animals heterozygous for the Hp mutation… CONTINUE READING
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