Distribution of human papillomavirus types in genital lesions from two temporally distinct populations determined by in situ hybridization.

@article{Anderson1993DistributionOH,
  title={Distribution of human papillomavirus types in genital lesions from two temporally distinct populations determined by in situ hybridization.},
  author={Shawn M Anderson and P K Brooke and S L van Eyck and H Noell and William J. Frable},
  journal={Human pathology},
  year={1993},
  volume={24 5},
  pages={547-53}
}
We examined 341 paraffin-embedded cervical tissues for human papillomavirus (HPV) DNA by in situ hybridization. The genital lesions examined represented tissue biopsies from two temporally distinct populations (1964 to 1965 and 1988 to 1989). Biotinylated probes to 14 different HPV types were used in our analysis: HPV types 6, 11, 16, 18, 31, 33, 35, 42, 43, 44, 45, 51, 52, and 56. The number of HPV DNA-positive specimens and the distributions of HPV types were similar for these two populations… CONTINUE READING