Distribution of histone deacetylases 1–11 in the rat brain

@article{Broide2007DistributionOH,
  title={Distribution of histone deacetylases 1–11 in the rat brain},
  author={Ron Shraga Broide and Jeff M. Redwine and Najla Aftahi and Warren G. Young and Floyd E. Bloom and Christopher. J. Winrow},
  journal={Journal of Molecular Neuroscience},
  year={2007},
  volume={31},
  pages={47-58}
}
Although protein phosphorylation has been characterized more extensively, modulation of the acetylation state of signaling molecules is now being recognized as a key means of signal transduction. The enzymes responsible for mediating these changes include histone acetyl transferases and histone deacetylases (HDACs). Members of the HDAC family of enzymes have been identified as potential therapeutic targets for diseases ranging from cancer to ischemia and neurode generation. We initiated a… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 144 CITATIONS, ESTIMATED Infinity% COVERAGE

144 Citations

01020'10'13'16'19
Citations per Year
Semantic Scholar estimates that this publication has 144 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-10 OF 50 REFERENCES

Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington’s disease

  • G. Gardian, L. Yang, C. Cleren, N Y.Calingasan, P. Klivenyi, M F.Beal
  • J. Biol
  • 2005
Highly Influential
4 Excerpts

Histone deacetylase activity and COPD, author reply

  • A Y.Lin
  • N. Engl. J. Med
  • 2005

Histone deacetylase inhibitors: latest developments, trends and prospects

  • O. Moradei, C R.Maroun, I. Paquin, A. Vaisburg
  • Curr. Med. Chem. AntiCancer Agents
  • 2005
1 Excerpt

Similar Papers

Loading similar papers…