Distribution of high chromogranin A serum levels in patients with nonmetastatic and metastatic prostate adenocarcinoma.

@article{Sciarra2009DistributionOH,
  title={Distribution of high chromogranin A serum levels in patients with nonmetastatic and metastatic prostate adenocarcinoma.},
  author={Alessandro Sciarra and Franco di Silverio and Ana Maria Autran and Stefano Salciccia and Alessandro Gentilucci and Andrea Alfarone and Vincenzo Gentile},
  journal={Urologia internationalis},
  year={2009},
  volume={82 2},
  pages={147-51}
}
OBJECTIVES We analyzed the incidence of elevated serum levels of chromogranin A (CgA) (as marker of neuroendocrine activity) in nonmetastatic and metastatic prostate cancer populations. MATERIAL AND METHODS 264 consecutive men with nonmetastatic prostate adenocarcinoma considered for radical prostatectomy (group 1) and 89 consecutive men with metastatic prostate adenocarcinoma (group 2) represented our population. In all 353 cases a blood sample for the determination of serum total PSA and… CONTINUE READING