Distribution of gastrin releasing peptide-bombesin-like immunostaining in rat brain

@article{Roth1982DistributionOG,
  title={Distribution of gastrin releasing peptide-bombesin-like immunostaining in rat brain},
  author={Kevin A. Roth and Eckard Weber and Jack David Barchas},
  journal={Brain Research},
  year={1982},
  volume={251},
  pages={277-282}
}
Several antisera were raised in rabbits against synthetic gastrin releasing peptide (1-27)(porcine) (GRP (1-27))and GRP (1-I 6). In immunohistochemical staining experiments on frozen brain sections from rats, the antisera raised against GRP (1-27) also labeled substance P neurons. This substance P-like immunostaining was selectively blocked by incubation of the sections with GRP(1-27) antiserum in the presence of an excess concentration (50/~M) of synthetic substance P. A residual… CONTINUE READING

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