Distribution of fitness effects among beneficial mutations before selection in experimental populations of bacteria

@article{Kassen2006DistributionOF,
  title={Distribution of fitness effects among beneficial mutations before selection in experimental populations of bacteria},
  author={Rees Kassen and Thomas Bataillon},
  journal={Nature Genetics},
  year={2006},
  volume={38},
  pages={484-488}
}
The extent to which a population diverges from its ancestor through adaptive evolution depends on variation supplied by novel beneficial mutations. Extending earlier work, recent theory makes two predictions that seem to be robust to biological details: the distribution of fitness effects among beneficial mutations before selection should be (i) exponential and (ii) invariant, meaning it is always exponential regardless of the fitness rank of the wild-type allele. Here we test these predictions… Expand

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