Distribution of detoxifying genes polymorphism in Maharastrian population of central India.

@article{Devi2008DistributionOD,
  title={Distribution of detoxifying genes polymorphism in Maharastrian population of central India.},
  author={Sivanesan Saravana Devi and Nadimuthu Vinayagamoorthy and Meenal G Agrawal and Arup Ratan Biswas and Raka A Biswas and Pravin Krishnarao Naoghare and Sreya Kumbhakar and Kannan Krishnamurthi and Jan G. Hengstler and Matthias Hermes and Tapan Chakrabarti},
  journal={Chemosphere},
  year={2008},
  volume={70 10},
  pages={1835-9}
}
The present study is aimed at evaluating the genotype frequency of detoxifying genes such as GSTM1, GSTT1 and NQO1 in Maharastrian population of central India. The study revealed about 64.6% of GSTM1-positive and 35.4% GSTM1-null population. GSTT1-positive genotype was found to be 87.5% and GSTT1-null showed 12.5%. The NQO1 genotype of Maharastrian population showed 52.3% of C/C, 42.48% C/T and 5.18% T/T. The NQO1 of this population does not deviate from the expected Hardy-Weinberg equilibrium… CONTINUE READING

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