Distribution of corticotropin-releasing hormone in the developing zebrafish brain.

@article{Chandrasekar2007DistributionOC,
  title={Distribution of corticotropin-releasing hormone in the developing zebrafish brain.},
  author={Gayathri Chandrasekar and Gilbert Lauter and Giselbert Hauptmann},
  journal={The Journal of comparative neurology},
  year={2007},
  volume={505 4},
  pages={337-51}
}
Corticotropin-releasing hormone (CRH) plays a central role in the physiological regulation of the hypothalamus-pituitary-adrenal/interrenal axis mediating endocrine, behavioral, autonomic, and immune responses to stress. Despite the wealth of knowledge about the physiological roles of CRH, the genetic mechanisms by which CRH neurons arise during development are poorly understood. As a first step toward analyzing the molecular and genetic pathways involved in CRH lineage specification, we… CONTINUE READING