Distribution of corticotropin-releasing factor in rat brain.

  title={Distribution of corticotropin-releasing factor in rat brain.},
  author={Mikl{\'o}s Palkovits and Michael J. Brownstein and Wylie Vale},
  journal={Federation proceedings},
  volume={44 1 Pt 2},
Corticotropin-releasing factor (CRF) has been measured in 70 brain nuclei and in the posterior pituitary of the rat by radioimmunoassay (RIA) developed against synthetic rat CRF. CRF-like immunoreactivity was detected in 32 brain areas in concentrations higher than 0.3 ng/mg protein. Most of the CRF in the brain was in the hypothalamus, where the highest… CONTINUE READING