Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin.

@article{Stnder2005DistributionOC,
  title={Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin.},
  author={Sonja St{\"a}nder and Martin Schmelz and Dieter Metze and Thomas Anton Luger and Roman R Rukwied},
  journal={Journal of dermatological science},
  year={2005},
  volume={38 3},
  pages={177-88}
}
BACKGROUND Cannabinoid receptors mediate the psychopharmacological action of marijuana and have been localized in the central and peripheral nervous system as well as on cells of the immune system. OBJECTIVE Up to now, two cannabinoid receptors (CB1 and CB2) have been cloned and recent studies on animal tissue gave evidence for the presence of cannabinoid receptors in the skin. METHODS In the present immunohistochemical investigation we determined the precise localization of CB1 and CB2 in… CONTINUE READING
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