Distribution of blood flow and ventilation in the lung : gravity is not the only factor

@inproceedings{Galvin2007DistributionOB,
  title={Distribution of blood flow and ventilation in the lung : gravity is not the only factor},
  author={Ivor Galvin and Gordon Blair Drummond and Mahesh Nirmalan},
  year={2007}
}
Current textbooks in anaesthesia describe how gravity affects the regional distribution of ventilation and blood flow in the lung, in terms of vertical gradients of pleural pressure and pulmonary vascular pressures. This concept fails to explain some of the clinical features of disturbed lung function. Evidence now suggests that gravity has a less important role in the variation of regional distribution than structural features of the airways and blood vessels. We review more recent studies… CONTINUE READING