[Distribution of atomic density in protein globules].


The distribution of atomic density in the elastase and subtilysin globulas was modeled on the basis of their x-ray atomic coordinates and was consequently investigated through comparison with the normal Poisson distribution, using the chi2-test. The results from the above procedure are discussed in connection with the concept of kinetic constraints on the globula folding process as well as with the enzyme-machine hypothesis. It is shown that the minimum average dimensions of atomic irregularities in the protein globula are about 200 A3.

Cite this paper

@article{Nedev1978DistributionOA, title={[Distribution of atomic density in protein globules].}, author={K N Nedev}, journal={Biofizika}, year={1978}, volume={23 4}, pages={602-4} }