Distribution of angiotensin II receptor subtypes in rat brain nuclei

  title={Distribution of angiotensin II receptor subtypes in rat brain nuclei},
  author={Nicholas Oberm{\"u}ller and Thomas Unger and Juraj Culman and Peter Gohlke and Marc de Gasparo and Serge Pierre Bottari},
  journal={Neuroscience Letters},
Angiotensin II (ANG II) receptor subtypes in rat brain were characterized and quantified by competitive radioligand binding using [125I]Sar1 Ile8 angiotensin II ([125I]sarilesin) as a tracer and ANG II, sarilesin and the subtype selective ligands DuP 753 (AT1) and CGP 42112A (AT2) as competitors. The distribution of AT1 and AT2 receptors was determined in midbrain, brainstem, hypothalamus as well as in individual hypothalamic and periventricular nuclei. Whereas in midbrain and brainstem the AT1… CONTINUE READING


Publications citing this paper.
Showing 1-6 of 6 extracted citations

The Nervous System and the Heart

Humana Press • 2000
View 10 Excerpts
Highly Influenced

Central angiotensin II receptors mediate hemodynamic response variability to stressors.

American journal of physiology. Regulatory, integrative and comparative physiology • 2006
View 2 Excerpts

Angiotensin Vol. I

Emaad M. Abdel-Rahman, Anthony Lloyd Albiston, +6 authors Bernward A. Sch6lkens
Handbook of Experimental Pharmacology • 2004

Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2003
View 2 Excerpts