Distribution of alkaline phosphatase, osteopontin, RANK ligand and osteoprotegerin in calcified human carotid atheroma.

Abstract

Ectopic vascular calcification is a significant component of atherosclerotic disease. Osteopontin (OPN), Osteoprotegerin (OPG), Receptor Activator of NFκB Ligand (RANKL), and alkaline phosphatase (ALP) are each thought to play central roles in the calcification or demineralization of atherosclerotic lesions. Abnormalities in the balance of these proteins… (More)
DOI: 10.1007/s10930-015-9620-3

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@article{Higgins2015DistributionOA, title={Distribution of alkaline phosphatase, osteopontin, RANK ligand and osteoprotegerin in calcified human carotid atheroma.}, author={Catherine L Higgins and Salim Isbilir and Pamela Basto and Iou Yih Chen and Muthiah Vaduganathan and Periyanan Vaduganathan and Michael J. Reardon and Gerald M. Lawrie and L. F. Peterson and Joel D. Morrisett}, journal={The protein journal}, year={2015}, volume={34 5}, pages={315-28} }