Distribution of adoptively transferred porcine T-lymphoblasts tracked by (18)F-2-fluoro-2-deoxy-D-glucose and position emission tomography.

@article{Eriksson2011DistributionOA,
  title={Distribution of adoptively transferred porcine T-lymphoblasts tracked by (18)F-2-fluoro-2-deoxy-D-glucose and position emission tomography.},
  author={Olof Eriksson and Arian M. Sadeghi and Bj{\"o}rn {\"O}stbring Carlsson and Torsten Eich and Torbj{\"o}rn Lundgren and Britten Nilsson and Thomas H. T{\"o}tterman and Olle Korsgren and Anders Sundin},
  journal={Nuclear medicine and biology},
  year={2011},
  volume={38 6},
  pages={
          827-33
        }
}
INTRODUCTION Autologous or allogeneic transfer of tumor-infiltrating T-lymphocytes is a promising treatment for metastatic cancers, but a major concern is the difficulty in evaluating cell trafficking and distribution in adoptive cell therapy. This study presents a method of tracking transfusion of T-lymphoblasts in a porcine model by (18)F-2-fluoro-2-deoxy-d-glucose ([(18)F]FDG) and positron emission tomography. METHODS T-lymphoblasts were labeled with the positron-emitting tracer [(18)F]FDG… CONTINUE READING
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