Distribution of adenosine receptors in the postmortem human brain: an extended autoradiographic study.

@article{Svenningsson1997DistributionOA,
  title={Distribution of adenosine receptors in the postmortem human brain: an extended autoradiographic study.},
  author={Per Svenningsson and H{\aa}kan Hall and G{\"o}ran Sedvall and Bertil B. Fredholm},
  journal={Synapse},
  year={1997},
  volume={27 4},
  pages={322-35}
}
Whole-hemisphere sections from six subjects were used in a quantitative autoradiographic study to characterize and to investigate the distribution of adenosine receptors, using [3H]DPCPX, [3H]CGS 21680, and [3H]SCH 58261 as radioligands. [3H]DPCPX-binding showed the pharmacology expected for adenosine A1 receptors and is therefore taken to mirror adenosine A1 receptors. Adenosine A1 receptors were widely distributed, with the highest densities in the stratum radiatum/pyramidale of the… CONTINUE READING

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