Distribution of Phlorotannins in the Brown Alga Ecklonia cava and Comparison of Pretreatments for Extraction

  title={Distribution of Phlorotannins in the Brown Alga Ecklonia cava and Comparison of Pretreatments for Extraction},
  author={Muhammad Tanvir Hossain Chowdhury and Issa Bangoura and Ji‐Young Kang and Nam Gyu Park and Dong Hyun Ahn and Yong-Ki Hong},
  journal={Fisheries and Aquatic Sciences},
The brown seaweed Ecklonia cava is known to be a rich source of phlorotannins that have diverse biological activities. Among the phlorotannins in E. cava, concentrations of dieckol and phlorofucofuroeckol-A, which were identified as major active components, were determined in different parts of the tissue. We compared the efficacy of different pretreatments for their extraction. A high- performance liquid chromatography (HPLC) method to determine phlorotannin concentrations showed good accuracy… 

Figures and Tables from this paper

Comparison of Ecklonia cava, Ecklonia stolonifera and Eisenia bicyclis for phlorotannin extraction.

Dieckol and PFE-A showed almost 9- and 7-fold stronger antioxidant activity than the standard butylhydroxytoluene, and 6-and 4-fold greater than L-ascorbic acid in molar concentration, respectively.

Preparation and chromatographic analysis of phlorotannins.

This review focuses on techniques for the extraction, isolation and chromatographic purification of approximately 150 phlorotannins during these four decades, due to the high structural diversity and classification of these polyphenols.

Effect of Food Preparations on In Vitro Bioactivities and Chemical Components of Fucus vesiculosus

The in vitro results suggest that the preparation of F. vesiculosus as a soup could have hypercholesterolemia lowering effect and the mode of preparation significantly influenced the final bioactivities.

Feeding the Abalone Haliotis discus hannai with the Seaweed Eisenia bicyclis Allows the Accumulation of Phlorotannins

R reverse-phase high-performance liquid chromatography was used to isolate and quantify phlorotannins, which were identified by mass spectrometry and [1H]-nuclear magnetic resonance to be the P1 compound, 7-phloroeckol, and eckol.

Dietary Intake and Accumulation of Phlorotannins in Abalone after Feeding the Phaeophyte Ecklonia stolonifera

Dietary intake and bioavailability of phorotannins in abalone was investigated after feeding with the phlorotannin-rich brown seaweed Ecklonia stolonifera after 4 days starvation. Reverse-phase

Bioactivity evaluation and composition of extracts from sub-Antarctic macroalgae Mazzaella laminarioides at distinct development phases

Sub-Antarctic macroalgae can be a feasible source of innumerous bioactive compounds that can display important biological activities. In this sense, the aims of this work were to evaluate the

In vitro screening of natural feed additives from crustaceans, diatoms, seaweeds and plant extracts to manipulate rumen fermentation.

ASC, LAM, CHI and IVY showed promising potential in vitro as feed additives to improve rumen function, thus more research is needed to investigate their mode of action in the rumen microbial ecosystem.

Aquatic Phlorotannins and Human Health: Bioavailability, Toxicity, and Future Prospects

Medicinal chemists and pharmacognosists have relied on terrestrial sources for bioactive phytochemicals to manage and treat disease conditions. However, minimal interest is given to sea life,




Local and chemical distribution of phlorotannins in brown algae

Phlorotannins were found to be accumulated within the vegetative cells of the outer cortical layer of the thalli, regardless of the species, stage of growth or organ.

Bactericidal activity of phlorotannins from the brown alga Ecklonia kurome.

The bactericidal effects of the phlorotannins were more pronounced than those of the catechins against food-borne pathogenic bacteria and were as effective against MRSA as against the other bacteria tested.

Anti-Allergic Phlorotannins from the Edible Brown Alga, Eisenia Arborea

Most of the phlorotannins exhibited activities similar to or greater than the typical inhibitor, epigallocatechin gallate, and Phlorofucofuroeckol-B showed the greatest activity among the tested phlorOTannins at 2.8 times greater than epigallsign gallate.

High-performance liquid chromatographic analysis of phlorotannins from the brown alga Fucus vesiculosus.

The separation of a set of individual soluble phlorotannins from the phenolic crude extract of Fucus vesiculosus was achieved by HPLC with UV photodiode array detection, demonstrating the suitability of the NP-HPLC method for mass spectrometric application.

A new assay for quantifying brown algal phlorotannins and comparisons to previous methods

A new assay in which 2,4-dimethoxybenzaldehyde (DMBA) reacts specifically with 1,3-and 1-3,5-substituted phenols (e.g., phlorotannins) to form a colored product is developed, which is inexpensive, rapid, and can be used with small sample volumes.

Isolation and identification of phlorotannins from Ecklonia stolonifera with antioxidant and anti-inflammatory properties.

Results suggest that phlorofucofuroeckol A has a potential for functional foods with antioxidant and anti-inflammatory activities.

Anti-HIV-1 activity of phloroglucinol derivative, 6,6'-bieckol, from Ecklonia cava.

Acetyl- and butyrylcholinesterase inhibitory activities of sterols and phlorotannins from Ecklonia stolonifera

It has been suggested that the inhibition of these enzymes by the sterols and phlorotannins derived from marine brown algae could be a useful approach for the treatment of Alzheimer’s disease.

Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation.

  • S. HeoSeok-Chun Ko Y. Jeon
  • Biology
    Toxicology in vitro : an international journal published in association with BIBRA
  • 2009