Distribution of P2Y receptor subtypes on haematopoietic cells.

@article{Jin1998DistributionOP,
  title={Distribution of P2Y receptor subtypes on haematopoietic cells.},
  author={Jianguo Jin and Venkata Ramesh Dasari and Frank D Sistare and Satya P Kunapuli},
  journal={British journal of pharmacology},
  year={1998},
  volume={123 5},
  pages={789-94}
}
1. RT-PCR-southern hybridization analyses with radiolabelled P2Y receptor cDNAs as probes indicated that the peripheral blood leukocytes and the human umbilical vein endothelial cells express P2Y1, P2Y2, P2Y4 and P2Y6 receptors. 2. Of the haematopoietic cell lines tested, promonocytic U937 cells express P2Y2 and P2Y6, but not P2Y1 or P2Y4; promyelocytic HL-60 cells express the P2Y1, P2Y2 and P2Y6 receptors but not the P2Y4 receptor; K562 cells express P2Y1 but not P2Y2, P2Y4 or P2Y6; and Dami… CONTINUE READING
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