Distribution of IL-31 and its receptor expressing cells in skin of atopic dermatitis.

@article{Kato2014DistributionOI,
  title={Distribution of IL-31 and its receptor expressing cells in skin of atopic dermatitis.},
  author={Atsuhiko Kato and Etsuko Fujii and Takeshi Watanabe and Yoshiaki Takashima and Hiroaki Matsushita and Takuya Furuhashi and Akimichi Morita},
  journal={Journal of dermatological science},
  year={2014},
  volume={74 3},
  pages={229-35}
}
BACKGROUND To understand the clinical segments of IL-31 signaling blockade therapy in pruritus of atopic dermatitis (AD), direct detection of the target proteins in the diseased tissues will provide crucial information. There is a lack of direct evidence concerning the cellular origin of IL-31 in AD skins, and data on the expression of IL-31RA in AD are inconsistent. Also, there is no available information regarding IL-31RA protein expression in human dorsal root ganglia (DRG), which mediates… CONTINUE READING